Efficacy and safety of antihypertensive drugs deprescribing in older adults: A systematic review and meta-analysis of randomized controlled trials
In older adults, a strategy of deprescribing antihypertensive drugs was not associated with an increased risk of mortality, MACE, or other SAEs. Despite that these findings provide reassuring evidence for deprescribing strategies, the current evidence base remains limited and uncertain, warranting caution and strict clinical monitoring.
Authors
- Ahmed K. Emara (ORCID: https://orcid.org/0000-0002-8421-7340)
- Abdullah M Alharran (ORCID: https://orcid.org/0009-0003-2337-6588)
- Shaikha J. Aldeyain
- Rawan A. Almutairi
- Amal A. Alsubaiei
- Izuddin A. Rawashdeh
- Saud A. Alyahya
- Abdel-Rahman Qamar
- Batoul H. Aljaber
- Mohammad F. Alenezi
Institutions
- Al-Azhar University (EG)
- Kuwait Institute for Medical Specialization (KW)
- Médecins Sans Frontières (FR)
- Arabian Gulf University (BH)
Publication Details
- Journal
- International Journal of Cardiology Cardiovascular Risk and Prevention
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1016/j.ijcrp.2025.200570
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00