Sex-specific transcriptome similarity networks elucidate comorbidity relationships

Our findings demonstrate that transcriptomic data can reveal sex-specific molecular links between diseases and suggest that biological sex should be considered in the design of therapeutic strategies and drug administration.

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Publication Details

Journal
Communications Medicine
Published
2025-12-30
DOI
https://doi.org/10.1038/s43856-025-01329-0
Citations
1
Primary Topic
Sex and Gender in Healthcare
Type
article
Field-Weighted Citation Impact
1.88
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article

Sex-specific transcriptome similarity networks elucidate comorbidity relationships

1 citations
Communications Medicine
Sex and Gender in Healthcare
1.88
article

Sex-specific transcriptome similarity networks elucidate comorbidity relationships

article en
1 citations

Abstract

Our findings demonstrate that transcriptomic data can reveal sex-specific molecular links between diseases and suggest that biological sex should be considered in the design of therapeutic strategies and drug administration.

Communications MedicineVol. 6(1)
Binghamton University (US), Universitat de València (ES), Universidade Católica Portuguesa (PT), Barcelona Supercomputing Center (ES), Centro de Investigación Biomédica en Red de Salud Mental (ES), Universidad Alfonso X el Sabio (ES), INCLIVA Health Research Institute (ES), Universitat Politècnica de Catalunya (ES)
Good health and well-being
Openalex Percentile: Top 10%
Sex and Gender in Healthcare
1.88
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