Inter-fractional Variation of Linear Energy Transfer Profiles During Carbon-ion Radiotherapy for Pancreatic Cancer

During CIRT for pancreatic cancer, inter-fractional variations in LET<sub>d</sub> profiles may be more pronounced at larger target volumes and at lower L<sub>X%</sub> values. Although the variations were modest in most cases, inter-fractional changes in bowel gas within the beam path are a potential risk factor for reduced LET<sub>d</sub> coverage.

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Journal
Anticancer Research
Published
2025-12-30
DOI
https://doi.org/10.21873/anticanres.17961
Primary Topic
Radiation Therapy and Dosimetry
Type
article
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article

Inter-fractional Variation of Linear Energy Transfer Profiles During Carbon-ion Radiotherapy for Pancreatic Cancer

Yuhei Miyasaka, Hanae Yoshida, YUKIHIKO YOSHIMATSU, TATSUYA OHNO et al.
Anticancer Research
Radiation Therapy and Dosimetry
article

Inter-fractional Variation of Linear Energy Transfer Profiles During Carbon-ion Radiotherapy for Pancreatic Cancer

Yuhei Miyasaka, Hanae Yoshida, YUKIHIKO YOSHIMATSU, TATSUYA OHNO, TAKAHIRO OIKE, MAKOTO SAKAI
article en

Abstract

During CIRT for pancreatic cancer, inter-fractional variations in LET<sub>d</sub> profiles may be more pronounced at larger target volumes and at lower L<sub>X%</sub> values. Although the variations were modest in most cases, inter-fractional changes in bowel gas within the beam path are a potential risk factor for reduced LET<sub>d</sub> coverage.

Anticancer ResearchVol. 46(1)
Kyushu University (JP), Gunma University (JP), Gunma University Hospital (JP), Hitachi (Japan) (JP)
Affordable and clean energy
Openalex Percentile: Top 27%
Radiation Therapy and Dosimetry
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