Effects of Remimazolam on Perioperative Inflammatory Response and Neurocognitive Disorders in Elderly Patients Undergoing Video-Assisted Thoracic Surgery: A Randomized Controlled Trial

Although remimazolam is less effective than propofol in suppressing the early postoperative inflammatory response in elderly patients undergoing VATS, it did not increase the risk of PND or infection. It has significant advantages in hemodynamic stability, facilitates faster recovery, and reduces injection pain, establishing it as a preferred anesthetic option for geriatric VATS, though its inflammatory mechanisms require clarification.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2025-12-01
DOI
https://doi.org/10.2147/dddt.s565045
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Effects of Remimazolam on Perioperative Inflammatory Response and Neurocognitive Disorders in Elderly Patients Undergoing Video-Assisted Thoracic Surgery: A Randomized Controlled Trial

Yingjie Ding, J. Li, Ping Yang, Yü Huang et al.
Drug Design Development and Therapy
Intensive Care Unit Cognitive Disorders
article

Effects of Remimazolam on Perioperative Inflammatory Response and Neurocognitive Disorders in Elderly Patients Undergoing Video-Assisted Thoracic Surgery: A Randomized Controlled Trial

Yingjie Ding, J. Li, Ping Yang, Yü Huang, Su Xiang, Chun Liu, Pengfei Pan, Juan Hu, Jinqiu Yang
article en

Abstract

Although remimazolam is less effective than propofol in suppressing the early postoperative inflammatory response in elderly patients undergoing VATS, it did not increase the risk of PND or infection. It has significant advantages in hemodynamic stability, facilitates faster recovery, and reduces injection pain, establishing it as a preferred anesthetic option for geriatric VATS, though its inflammatory mechanisms require clarification.

Drug Design Development and TherapyVol. Volume 19
Chongqing Three Gorges Central Hospital (CN), Chongqing Three Gorges University (CN)
Chongqing University
Good health and well-being
Openalex Percentile: Top 31%
Intensive Care Unit Cognitive Disorders
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