Paucimannosylation Is a Prognostic Marker in High-grade Serous Ovarian Cancer

Paucimannosylation, indicated by the presence of PMEs, is present in both tumor and immune cells in high-grade serous ovarian cancer. The prognostic implication of PMEs seems to be cell type-dependent. While immune cell paucimannosylation was associated with improved survival, tumor cell paucimannosylation was associated with reduced survival.

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Publication Details

Journal
Anticancer Research
Published
2025-12-30
DOI
https://doi.org/10.21873/anticanres.17925
Primary Topic
Proteoglycans and glycosaminoglycans research
Type
article
Field-Weighted Citation Impact
0.00

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article

Paucimannosylation Is a Prognostic Marker in High-grade Serous Ovarian Cancer

Dominique Könsgen, Lucia Otten, Carolin Schröder, Eva Maria Egger et al.
Anticancer Research
Proteoglycans and glycosaminoglycans research
article

Paucimannosylation Is a Prognostic Marker in High-grade Serous Ovarian Cancer

Dominique Könsgen, Lucia Otten, Carolin Schröder, Eva Maria Egger, Thore Thiesler, Michael H. Muders, Sarah Förster, ALEXANDER MUSTEA, LINA ADLOFF, MILKA MARINOVA
article en

Abstract

Paucimannosylation, indicated by the presence of PMEs, is present in both tumor and immune cells in high-grade serous ovarian cancer. The prognostic implication of PMEs seems to be cell type-dependent. While immune cell paucimannosylation was associated with improved survival, tumor cell paucimannosylation was associated with reduced survival.

Anticancer ResearchVol. 46(1)
University Hospital Bonn (DE)
Rheinische Friedrich-Wilhelms-Universität Bonn
Good health and well-being
Openalex Percentile: Top 33%
Proteoglycans and glycosaminoglycans research
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