Diagnostic Value of Peak-to-Basal Difference or Ratio of Growth Hormone in Children with Growth Hormone Deficiency

To the best of our knowledge, ΔGH has been explored only in a limited number of studies. This study investigated diagnostic accuracy of difference (ΔGH) or ratio of peak-to-basal GH on a large cohort of children with short stature. The supportive diagnostic performance observed in our cohort suggests that ΔGH is clinically useful in routine practice.

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Publication Details

Journal
Journal of Clinical Research in Pediatric Endocrinology
Published
2025-12-30
DOI
https://doi.org/10.4274/jcrpe.galenos.2025.2025-10-26
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
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article

Diagnostic Value of Peak-to-Basal Difference or Ratio of Growth Hormone in Children with Growth Hormone Deficiency

Özge Köprülü, Hüseyin Anıl Korkmaz, Behzat Özkan, Özlem Nalbantoğlu et al.
Journal of Clinical Research in Pediatric Endocrinology
Growth Hormone and Insulin-like Growth Factors
article

Diagnostic Value of Peak-to-Basal Difference or Ratio of Growth Hormone in Children with Growth Hormone Deficiency

Özge Köprülü, Hüseyin Anıl Korkmaz, Behzat Özkan, Özlem Nalbantoğlu, Elif Gökçe Basa, Fatma Yavuzyılmaz Şimşek, İbrahim Mert Erbaş
article en

Abstract

To the best of our knowledge, ΔGH has been explored only in a limited number of studies. This study investigated diagnostic accuracy of difference (ΔGH) or ratio of peak-to-basal GH on a large cohort of children with short stature. The supportive diagnostic performance observed in our cohort suggests that ΔGH is clinically useful in routine practice.

Journal of Clinical Research in Pediatric EndocrinologyVol. 18(1)
Izmir University (TR), University of Health Science (KH), Dr. Behçet Uz Çocuk Hastalıkları Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), University of Health Sciences Antigua (AG)
Zero hunger
Openalex Percentile: Top 29%
Growth Hormone and Insulin-like Growth Factors
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