Effect of Pathological Response After Neoadjuvant Chemotherapy on Long-term Outcomes in Locally Advanced Colorectal Cancer: A Japanese Multicenter Study

Patients with a good response to NAC tended to have a better prognosis. Adjuvant chemotherapy might improve outcomes in patients with poor response to NAC.

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Publication Details

Journal
Anticancer Research
Published
2025-12-30
DOI
https://doi.org/10.21873/anticanres.17947
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
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article

Effect of Pathological Response After Neoadjuvant Chemotherapy on Long-term Outcomes in Locally Advanced Colorectal Cancer: A Japanese Multicenter Study

Rika Ono, Tetsuro Tominaga, Kaido Oishi, Mariko Yamashita et al.
Anticancer Research
Colorectal Cancer Surgical Treatments
article

Effect of Pathological Response After Neoadjuvant Chemotherapy on Long-term Outcomes in Locally Advanced Colorectal Cancer: A Japanese Multicenter Study

Rika Ono, Tetsuro Tominaga, Kaido Oishi, Mariko Yamashita, Toshio Shiraishi, Shintaro Hashimoto, Shoko TEI, Masaki Kunizaki, Keisuke Nöda, Mitsutoshi Ishii, Ayano Inao, MASAAKI MORIYAMA, KEITARO MATSUMOTO, HIROSHI MARUTA, TAKASHI NONAKA, TAKASHI ONODA
article en

Abstract

Patients with a good response to NAC tended to have a better prognosis. Adjuvant chemotherapy might improve outcomes in patients with poor response to NAC.

Anticancer ResearchVol. 46(1)
Sasebo City General Hospital (JP), Nagasaki Ajisai Hospital (JP), Nagasaki Medical Center (JP), Ureshino Medical Center (JP), Nagasaki University Hospital (JP), Nagasaki University (JP)
No poverty
Openalex Percentile: Top 30%
Colorectal Cancer Surgical Treatments
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