Design characteristics of sequential multiple assignment randomised trials (SMARTs) for human health: a scoping review of studies between 2009 and 2024
Despite the increased adoption of SMART designs, substantial reporting variability persists. Most primary analyses underuse the capability of SMARTs to generate data for developing DTRs. SMART-specific standardised reporting guidelines can help accelerate the scientific and clinical impact of SMARTs.
Authors
- Sydney E. Browder (ORCID: https://orcid.org/0000-0002-2109-0434)
- Anastasia Ivanova (ORCID: https://orcid.org/0000-0003-4321-2073)
- Katharine L. McGinigle (ORCID: https://orcid.org/0000-0002-0706-159X)
- Bryce Rowland (ORCID: https://orcid.org/0000-0002-8900-6905)
- Michael R. Kosorok (ORCID: https://orcid.org/0000-0002-6070-9738)
- Christina W. Zhou
- Kevin J. Anstrom (ORCID: https://orcid.org/0000-0001-6452-2172)
- ANNA KAHKOSKA
- Elaine Jones
- Margaret Hoch
- Alice Kim
- Nikki L. B. Freeman
Institutions
- University of North Carolina at Chapel Hill (US)
- Duke University (US)
- Clinical Research Institute (US)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/bmjopen-2025-105506
- Primary Topic
- Statistical Methods in Clinical Trials
- Type
- article
- Field-Weighted Citation Impact
- 0.00