Nonhematopoietic MicroRNA-26b <sup>−/−</sup> Augments Atherosclerosis Development by Increasing Endothelial Inflammation and Leukocyte Adhesion—Brief Report

Our findings highlight that nonhematopoietic miR-26b plays a protective role in atherosclerosis by modulating endothelial cell function, suggesting potential therapeutic applications for miR-26b mimics in cardiovascular disease management.

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Publication Details

Journal
Arteriosclerosis Thrombosis and Vascular Biology
Published
2025-12-30
DOI
https://doi.org/10.1161/atvbaha.125.323888
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

Nonhematopoietic MicroRNA-26b −/− Augments Atherosclerosis Development by Increasing Endothelial Inflammation and Leukocyte Adhesion—Brief Report

Linsey J. F. Peters, Erik A.L. Biessen, Alexander Jans, Emiel P. C. van der Vorst et al.
Arteriosclerosis Thrombosis and Vascular Biology
MicroRNA in disease regulation
article

Nonhematopoietic MicroRNA-26b −/− Augments Atherosclerosis Development by Increasing Endothelial Inflammation and Leukocyte Adhesion—Brief Report

Linsey J. F. Peters, Erik A.L. Biessen, Alexander Jans, Emiel P. C. van der Vorst, Markus Haberbosch, Kiril Bidzhekov, Cheng Lin, Remco T. A. Megens, Matthias Bartneck, C. Weber, Yvonne Jansen, H. Jin, Yvonne Döring
article en

Abstract

Our findings highlight that nonhematopoietic miR-26b plays a protective role in atherosclerosis by modulating endothelial cell function, suggesting potential therapeutic applications for miR-26b mimics in cardiovascular disease management.

Arteriosclerosis Thrombosis and Vascular BiologyVol. 46(3)
University of Bern (CH), Bern University of Applied Sciences (CH), Maastricht University Medical Centre (NL), University Hospital of Bern (CH), Tianjin Medical University General Hospital (CN), Maastricht University (NL), DWI – Leibniz Institute for Interactive Materials (DE), Munich Cluster for Systems Neurology (DE), Universitätsklinikum Aachen (DE), German Centre for Cardiovascular Research (DE), Ludwig-Maximilians-Universität München (DE), RWTH Aachen University (DE)
Openalex Percentile: Top 33%
MicroRNA in disease regulation
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Nonhematopoietic MicroRNA-26b <sup>−/−</sup> Augments Atherosclerosis Development by Increasing Endothelial Inflammation and Leukocyte Adhesion—Brief Report — Linsey J. F. Peters, Erik A.L. Biessen, et al. · Arteriosclerosis Thrombosis and Vascular Biology (2025) | TGRS Research Map | TGRS