Direct construction of high-value pyridine scaffolds through manganese-promoted alkene dicarbofunctionalization
A versatile Mn-mediated dicarbofunctionalization enables efficient access to pharmaceutically relevant γ-heterocyclic ketones, α-tetralones, tetrahydroquinolines and benz[h]isoquinolines. An electrochemical alternative reduces Mn usage.
Authors
- Pierre‐Adrien Payard (ORCID: https://orcid.org/0000-0001-5661-6128)
- Lionel Perrin (ORCID: https://orcid.org/0000-0002-0702-8749)
- Julien Vantourout
- Ming-Yu Chen
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Syngenta (Switzerland) (CH)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1039/d5qo01424g
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00