17β-Hydroxysteroid dehydrogenases 1 and 2: potential markers for breast cancer recurrence and tamoxifen resistance among premenopausal women diagnosed with breast cancer in Denmark

HSD17B1 may be a prognostic marker for recurrence and HSD17B2 may be predictive of response to tamoxifen therapy in breast cancer.

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Publication Details

Journal
Breast Cancer Research
Published
2025-12-30
DOI
https://doi.org/10.1186/s13058-025-02196-2
Primary Topic
Estrogen and related hormone effects
Type
article
Field-Weighted Citation Impact
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article

17β-Hydroxysteroid dehydrogenases 1 and 2: potential markers for breast cancer recurrence and tamoxifen resistance among premenopausal women diagnosed with breast cancer in Denmark

Kristina Bang Christensen, Lindsay Jane Collin, Lauren E. McCullough, Henrik Toft Sørensen et al.
Breast Cancer Research
Estrogen and related hormone effects
article

17β-Hydroxysteroid dehydrogenases 1 and 2: potential markers for breast cancer recurrence and tamoxifen resistance among premenopausal women diagnosed with breast cancer in Denmark

Kristina Bang Christensen, Lindsay Jane Collin, Lauren E. McCullough, Henrik Toft Sørensen, Timothy L. Lash, Peer Christiansen, S. Hamilton-Dutoit, Kristina Lystlund Lauridsen, L. Waller, Kirsten M. Woolpert, Deirdre Cronin‐Fenton, Thomas P. Ahern, P. Damkier, Anders Kjærsgaard, Michael Goodman, Bent Ejlertsen
article en

Abstract

HSD17B1 may be a prognostic marker for recurrence and HSD17B2 may be predictive of response to tamoxifen therapy in breast cancer.

Breast Cancer ResearchVol. 28(1)
University of Vermont (US), University of Copenhagen (DK), Emory University (US), University of Southern Denmark (DK), Odense University Hospital (DK), Aarhus University Hospital (DK), Copenhagen University Hospital (DK), Danish Breast Cancer Cooperative Group (DK)
Good health and well-being
Openalex Percentile: Top 24%
Estrogen and related hormone effects
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17β-Hydroxysteroid dehydrogenases 1 and 2: potential markers for breast cancer recurrence and tamoxifen resistance among premenopausal women diagnosed with breast cancer in Denmark — Kristina Bang Christensen, Lindsay Jane Collin, et al. · Breast Cancer Research (2025) | TGRS Research Map | TGRS