Associations between lifetime history of depression, prenatal OXTR DNA methylation and breastfeeding outcomes
This highly novel study highlights the intriguing possibility that maternal prenatal DNA methylation at genes important for breastfeeding may be associated with breastfeeding experiences. Further understanding of vastly differing breastfeeding experiences would assist with the targeting efforts to support breastfeeding women, particularly those who are vulnerable, such as mothers who have depression.
Authors
- Robert Lyle (ORCID: https://orcid.org/0000-0001-6317-732X)
- Chris Murgatroyd (ORCID: https://orcid.org/0000-0002-6885-7794)
- Ziada Ayorech (ORCID: https://orcid.org/0000-0002-8372-421X)
- Aurora Oftedal (ORCID: https://orcid.org/0000-0003-1598-8771)
- Anne Kaasen (ORCID: https://orcid.org/0000-0001-9291-0105)
- Mona Bekkhus (ORCID: https://orcid.org/0000-0002-4447-8909)
- Christian M. Page (ORCID: https://orcid.org/0000-0002-1897-3666)
- Kristine L. Haftorn (ORCID: https://orcid.org/0000-0002-2152-1839)
- Elizabeth Braithwaite
Institutions
- Manchester Metropolitan University (GB)
- Oslo University Hospital (NO)
- Norwegian Institute of Public Health (NO)
- OsloMet – Oslo Metropolitan University (NO)
- University of Oslo (NO)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1186/s13148-025-02030-8
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 0.00