Clinical characteristics of post-operative N2 nodal upstaging in non-small cell lung cancer: a retrospective cohort study

Among patients with N2 NSCLC, N2 nodal upstaging-often due to small or inaccessible lymph nodes-did not significantly impact 5-year overall survival but was associated with improved PFS. These findings reinforce the clinical value of EBUS-TBNA as an effective tool for preoperative mediastinal staging in NSCLC despite its limitations in detecting small or inaccessible lymph nodes.

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Publication Details

Journal
Translational Lung Cancer Research
Published
2025-12-01
DOI
https://doi.org/10.21037/tlcr-2025-531
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical characteristics of post-operative N2 nodal upstaging in non-small cell lung cancer: a retrospective cohort study

Sun Young Choi, Y. I. Kim, Myung Jin Song, Jae Ho Lee et al.
Translational Lung Cancer Research
Lung Cancer Diagnosis and Treatment
article

Clinical characteristics of post-operative N2 nodal upstaging in non-small cell lung cancer: a retrospective cohort study

Sun Young Choi, Y. I. Kim, Myung Jin Song, Jae Ho Lee, Sukki Cho, Lee Ct, Sung Yoon Lim, Jong Sun Park, Byung Soo Kwon
article en

Abstract

Among patients with N2 NSCLC, N2 nodal upstaging-often due to small or inaccessible lymph nodes-did not significantly impact 5-year overall survival but was associated with improved PFS. These findings reinforce the clinical value of EBUS-TBNA as an effective tool for preoperative mediastinal staging in NSCLC despite its limitations in detecting small or inaccessible lymph nodes.

Translational Lung Cancer ResearchVol. 14(12)
Seoul National University Bundang Hospital (KR), Kangbuk Samsung Hospital (KR), Sungkyunkwan University (KR)
Good health and well-being
Openalex Percentile: Top 27%
Lung Cancer Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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Clinical characteristics of post-operative N2 nodal upstaging in non-small cell lung cancer: a retrospective cohort study — Sun Young Choi, Y. I. Kim, et al. · Translational Lung Cancer Research (2025) | TGRS Research Map | TGRS