Speech Biomarkers From Smartphone Calls Track Progression in <scp>REM</scp> Sleep Behavior Disorder and Parkinson's Disease
The phone call analysis requiring no patient effort or clinical supervision can detect speech decline in prodromal and early synucleinopathies, providing a potential paradigm shift for clinical trial design and neuroprotective intervention end points. ANN NEUROL 2026;99:935-948.
Authors
- Jan Švihlík (ORCID: https://orcid.org/0000-0002-1593-7424)
- Karel Šonka (ORCID: https://orcid.org/0000-0001-5773-9656)
- Michal Šimek
- Tereza Tykalová (ORCID: https://orcid.org/0000-0003-1156-3709)
- Jan Rusz (ORCID: https://orcid.org/0000-0002-1036-3054)
- Martin Šubert (ORCID: https://orcid.org/0000-0003-4710-8564)
- Evžen Růžička (ORCID: https://orcid.org/0000-0002-4893-9661)
- Michal Novotný (ORCID: https://orcid.org/0000-0001-5608-4029)
- Pavel Sovka
- Vojtěch Illner
- Petr Dušek
- Tomáš Kouba
Institutions
- Charles University (CZ)
- Czech Technical University in Prague (CZ)
- University of Chemistry and Technology, Prague (CZ)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1002/ana.78140
- Primary Topic
- Voice and Speech Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- České Vysoké Učení Technické v Praze
- European Commission