CXCR4-engineered fibroblast membrane nanovesicles for Photothermal-enhanced ferroptotic therapy through chemokine-navigated tumor homing
Fibroblast membrane engineering, combined with chemokine-gradient navigation and photothermally controlled therapeutic activation, represents the translational potential of nanomedicine in clinical by developing precision nanomedicines that coordinate biological recognition with stimulus-responsive bioactivity.
Authors
- Li-fen Zhang
- Yunzhi Liu (ORCID: https://orcid.org/0000-0003-0524-4023)
- Tan Ya-nan
- S. Kong
- Yu-Ma Yang
- Victor Lee (ORCID: https://orcid.org/0000-0002-6283-978X)
- Min Luo (ORCID: https://orcid.org/0000-0002-5276-9327)
- Jie Luo
- Lu Bai
- Xin-Yuan Guan
Institutions
- Ji Hua Laboratory (CN)
- University of Hong Kong - Shenzhen Hospital (CN)
- HKU-Pasteur Research Pole (HK)
- University of Hong Kong (HK)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1186/s12951-025-03951-5
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00