Combination of EGCG and BH3 Mimetic Inhibitor Enhances Apoptosis of MCF-7 and MDA-MB-231 Cancer Cells

EGCG has been shown to possess antitumor properties in breast cancer cells. Moreover, EGCG has the potential to enhance the apoptotic effects of ABT-737 by suppressing the expression of Mcl-1.

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Publication Details

Journal
Advanced Biomedical Research
Published
2025-12-01
DOI
https://doi.org/10.4103/abr.abr_425_24
Primary Topic
Tea Polyphenols and Effects
Type
article
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article

Combination of EGCG and BH3 Mimetic Inhibitor Enhances Apoptosis of MCF-7 and MDA-MB-231 Cancer Cells

Zahra Sadat Miri, Hossein Bagheri, Alireza Amani, Hadi Karami
Advanced Biomedical Research
Tea Polyphenols and Effects
article

Combination of EGCG and BH3 Mimetic Inhibitor Enhances Apoptosis of MCF-7 and MDA-MB-231 Cancer Cells

Zahra Sadat Miri, Hossein Bagheri, Alireza Amani, Hadi Karami
article en

Abstract

EGCG has been shown to possess antitumor properties in breast cancer cells. Moreover, EGCG has the potential to enhance the apoptotic effects of ABT-737 by suppressing the expression of Mcl-1.

Advanced Biomedical ResearchVol. 14(1)
Arak University of Medical Sciences (IR), Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 29%
Tea Polyphenols and Effects
DOIOpen Access PDFOpenAlex
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Combination of EGCG and BH3 Mimetic Inhibitor Enhances Apoptosis of MCF-7 and MDA-MB-231 Cancer Cells — Zahra Sadat Miri, Hossein Bagheri, et al. · Advanced Biomedical Research (2025) | TGRS Research Map | TGRS