Exploring an independent association between rituximab‐cyclophosphamide‐doxorubicin‐vincristine‐prednisolone dose intensity and clinical outcomes in large B‐cell lymphoma: Analyses of subsequent endpoints following a complete response in a real‐world

Focusing on long-term outcomes after CR, this study demonstrates an increased risk of relapse when R-CHOP intensity is reduced, providing novel evidence that complements the association between reduced treatment intensity and inferior LBCL outcomes.

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Publication Details

Journal
Cancer
Published
2025-12-30
DOI
https://doi.org/10.1002/cncr.70248
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploring an independent association between rituximab‐cyclophosphamide‐doxorubicin‐vincristine‐prednisolone dose intensity and clinical outcomes in large B‐cell lymphoma: Analyses of subsequent endpoints following a complete response in a real‐world

Esra Terzi Demirsoy, Fatma Keklik Karadağ, Işık Atagündüz, Eda Nuhoğlu Kantarcı et al.
Cancer
Lymphoma Diagnosis and Treatment
article

Exploring an independent association between rituximab‐cyclophosphamide‐doxorubicin‐vincristine‐prednisolone dose intensity and clinical outcomes in large B‐cell lymphoma: Analyses of subsequent endpoints following a complete response in a real‐world

Esra Terzi Demirsoy, Fatma Keklik Karadağ, Işık Atagündüz, Eda Nuhoğlu Kantarcı, Meral Uluköylü Mengüç, Deniz Gören, Elif Birtaş ATEŞOĞLU, Ebru Pekgüç, GÜRAY SAYDAM, Abdülkadir Şahin, Emre Osmanbaşoğlu, Derya Demir, Asu Fergün Yılmaz, Metban Mastanzade, Murat Özbalak, Serdar Örnek, Burhan Ferhanoğlu, Muhlis Cem Ar, Ozgur MEHTAP, Kıvanç Koruk, Umut Yılmaz, Tayfur Toptaş, Nazik Okumus, Meltem Olga Akay, Turgay Ulaş, Öner Doğan, Tuğba Zorlu, Merve Apaydın Kayer, Fevzi Altuntaş, Ahmet Bahadır Ak, Taner Tan, Uğur Hatipoğlu, Deram Büyüktaş, Tuğrul Elverdi, Mert Seyhan, Sinem Civriz Bozdağ, Ali Durdu, Mehmet Sinan Dal
article en

Abstract

Focusing on long-term outcomes after CR, this study demonstrates an increased risk of relapse when R-CHOP intensity is reduced, providing novel evidence that complements the association between reduced treatment intensity and inferior LBCL outcomes.

CancerVol. 132(1)
Yeditepe University (TR), Koç University (TR), Haliç University (TR), Ege University (TR), Ankara Onkoloji Eğitim ve Araştırma Hastanesi (TR), Memorial Sisli Hospital (TR), Istanbul University-Cerrahpaşa (TR), Sağlık Bilimleri Üniversitesi (TR), Ankara Yıldırım Beyazıt University (TR), Amerikan Hastanesi (TR), Kocaeli Üniversitesi (TR), Istanbul University (TR), Marmara University (TR)
Türk Hematoloji Derneği
Good health and well-being
Openalex Percentile: Top 29%
Lymphoma Diagnosis and Treatment
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