The medial septal–medial habenula cholinergic circuit: A new mechanism of exercise improving cognitive function in AD mice
Exercise, mediated by the MS-MHb cholinergic circuit, improved neuronal damage and cognitive function in AD mice. This study provides scientific evidence for the potential application of exercise in the prevention and control of AD and offers new insights for future clinical intervention strategies from the perspective of neuroscience.
Authors
- Wujing Ren (ORCID: https://orcid.org/0000-0002-6098-2910)
- Zhenjun Tian (ORCID: https://orcid.org/0000-0003-4047-9194)
- Liye Zou (ORCID: https://orcid.org/0000-0001-6411-5710)
- Jue Chen (ORCID: https://orcid.org/0000-0003-2075-4283)
- Xu Wen
- Lili Zhang
- Yifang Zhao
- Tao Wang
- Xiaochun Wang
- Lili Feng
Institutions
- Shenzhen University (CN)
- Shanghai University of Sport (CN)
- Zhejiang University (CN)
- Shaanxi Normal University (CN)
Publication Details
- Journal
- Journal of sport and health science/Journal of Sport and Health Science
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jshs.2025.101118
- Primary Topic
- Nicotinic Acetylcholine Receptors Study
- Type
- article
- Field-Weighted Citation Impact
- 0.00