Sugammadex versus Neostigmine Reversal After Thoracoscopic Thymectomy in Myasthenia Gravis: A Multicenter, Randomized Controlled Trial
In patients with MG undergoing VATS thymectomy, this pragmatic trial simulating routine practice demonstrates that sugammadex provides faster and more reliable reversal of moderate neuromuscular blockade (median TOF count 3) than neostigmine, leading to clinically meaningful reductions in recovery time (by 12.01 minutes), extubation time, and rNMB incidence.
Authors
- Y H Wang
- Yingjie Du (ORCID: https://orcid.org/0000-0002-3454-6939)
- Shaofei Su (ORCID: https://orcid.org/0000-0002-9299-8853)
- Guyan Wang
- Chunhua Xi
- Lili Wu
- Shijiang Liu
- Hongya Chen
- Chunhua Hu
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Beijing Obstetrics and Gynecology Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/dddt.s573927
- Primary Topic
- Myasthenia Gravis and Thymoma
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wu Jieping Medical Foundation