Development and multicenter external validation of an intratumoral and peritumoral ultrasound-based radiomics model for preoperative prediction of HER2 status in IHC 2 + breast cancer
A nomogram combining US-based intratumoral and peritumoral radiomics features with key clinical variables showed potential utility for noninvasive, preoperative prediction of HER2 status in patients with IHC 2 + breast cancer and may assist in individualized treatment planning.
Authors
- Yayun Chen Ning Lin
- Xiaoli Cao (ORCID: https://orcid.org/0000-0001-5928-6304)
- J Wang (ORCID: https://orcid.org/0009-0007-1468-5214)
- Yu Cui (ORCID: https://orcid.org/0000-0002-4925-1500)
- Nina Qu
- Can Liu
Institutions
- Qingdao University (CN)
- Shandong University of Aeronautics (CN)
- Yuhuangding Hospital (CN)
- Yantaishan Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1186/s40001-025-03698-7
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00