Cross-reactive immunity within pneumococcal serogroups: Implications for next-generation vaccine development
The inhibition OPA enabled a precise assessment of serogroup-level cross-reactive immunity, revealing heterogeneous patterns of cross-reactivity. These findings underscore the need for careful serotype selection and epitope evaluation in next-generation vaccine formulations.
Authors
- Min Joo Choi (ORCID: https://orcid.org/0000-0002-2739-0948)
- A-Yeung Jang (ORCID: https://orcid.org/0000-0002-4050-2107)
- Hyun Ji
- Hee Jin Cheong
- Ho Seong Seo
- Yu Jung Choi
- Joon Young Song
- Eun Hye Kang
Institutions
- Korea Atomic Energy Research Institute (KR)
- Korea University (JP)
Publication Details
- Journal
- Vaccine
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1016/j.vaccine.2025.128179
- Citations
- 2
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.71