Immune Checkpoint-Related Gene Polymorphisms and High Serum Concentration of PD-L1 and CTLA4 Contribute to the Resistance to Platinum-Based Chemotherapy in Cervical Cancer

The <i>PDCD1</i>- rs2227982, <i>CD274</i>-rs2890658 and <i>CTLA4</i>- rs3087243 polymorphisms and high serum levels of PD-L1 and CTLA4 may predict chemotherapy resistance in cervical cancer patients.

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Publication Details

Journal
International Journal of Women s Health
Published
2025-12-01
DOI
https://doi.org/10.2147/ijwh.s569408
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
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article

Immune Checkpoint-Related Gene Polymorphisms and High Serum Concentration of PD-L1 and CTLA4 Contribute to the Resistance to Platinum-Based Chemotherapy in Cervical Cancer

Hongqin Yuan, Kaidong Liu, Jia Zhang, Pei Wang et al.
International Journal of Women s Health
Cancer Immunotherapy and Biomarkers
article

Immune Checkpoint-Related Gene Polymorphisms and High Serum Concentration of PD-L1 and CTLA4 Contribute to the Resistance to Platinum-Based Chemotherapy in Cervical Cancer

Hongqin Yuan, Kaidong Liu, Jia Zhang, Pei Wang, Xinfeng Wang
article en

Abstract

The <i>PDCD1</i>- rs2227982, <i>CD274</i>-rs2890658 and <i>CTLA4</i>- rs3087243 polymorphisms and high serum levels of PD-L1 and CTLA4 may predict chemotherapy resistance in cervical cancer patients.

International Journal of Women s HealthVol. Volume 17
Shanxi Provincial Cancer Hospital (CN)
Good health and well-being
Openalex Percentile: Top 30%
Cancer Immunotherapy and Biomarkers
DOIOpen Access PDFOpenAlex
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Immune Checkpoint-Related Gene Polymorphisms and High Serum Concentration of PD-L1 and CTLA4 Contribute to the Resistance to Platinum-Based Chemotherapy in Cervical Cancer — Hongqin Yuan, Kaidong Liu, et al. · International Journal of Women s Health (2025) | TGRS Research Map | TGRS