The clinical efficacy and pathological assessment of neoadjuvant imatinib treatment in patients with primary gastrointestinal stromal tumors

Pre-neoadjuvant tumor size, tumor location, mitotic count, and post-operative imatinib treatment were identified as prognostic factors for GIST patients who received NAT. Pathological regression was associated with radiological changes in the tumor, but it was not correlated with long-term patient prognosis.

Authors

Institutions

Publication Details

Journal
Journal of Gastrointestinal Oncology
Published
2025-12-01
DOI
https://doi.org/10.21037/jgo-2025-538
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The clinical efficacy and pathological assessment of neoadjuvant imatinib treatment in patients with primary gastrointestinal stromal tumors

X. Wang, X. Zhang, C C Shou, Jiren Yu et al.
Journal of Gastrointestinal Oncology
Gastrointestinal Tumor Research and Treatment
article

The clinical efficacy and pathological assessment of neoadjuvant imatinib treatment in patients with primary gastrointestinal stromal tumors

X. Wang, X. Zhang, C C Shou, Jiren Yu, Qing Zhang, Weili Yang
article en

Abstract

Pre-neoadjuvant tumor size, tumor location, mitotic count, and post-operative imatinib treatment were identified as prognostic factors for GIST patients who received NAT. Pathological regression was associated with radiological changes in the tumor, but it was not correlated with long-term patient prognosis.

Journal of Gastrointestinal OncologyVol. 16(6)
First Affiliated Hospital Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 26%
Gastrointestinal Tumor Research and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.