278 A Review of the Impact of Dietary Intervention as Part of a Novel ‘shape Up 4 Cancer Surgery’ Programme on Nutritional Status in Upper Gastrointestinal Cancer Patients

Abstract Aim To evaluate the impact of dietary intervention on upper gastrointestinal (UGI) cancer patients within a novel ‘shape up 4 cancer surgery’ (SU4CS) programme. Patient-generated subjective global assessment (PG-SGA), a questionnaire to evaluate weight change, food intake and symptoms, was used to assesses nutritional status. Method An 18-month pilot SU4CS programme, funded by Macmillan Cancer Support, ran between 2023-2025. Patients received holistic assessment including dietetic interventions, psychological assessment, and personalised exercise plans in partnership with Local Council services, which continued during neoadjuvant treatments. PG-SCA scores were captured at referral, initial SU4CS clinic assessment, preoperatively and at 6 months post operatively. Results Of 329 patients referred into SU4CS, 79 had an UGI cancer diagnosis. 71 attended the SU4CS clinic and 68 completed the programme. 62 (87%) patients were assessed by the SU4CS dietitian and underwent tailored interventions. 55 patients (81%) completed questionnaires preoperatively. PG -SGA scores deteriorated between referral and clinic assessment, but improved during the SU4CS programme:PG-SGA score0-34-8 (moderate malnutrition)9+ (severe malnutrition)Not completedOn referral (n=79)27 (34%)46 (58%)6 (8%)0In SU4CS clinic (n=71)16 (23%)21 (30%)34 (47%)0Pre operatively (n=68)33 (49%)21 (31%)1 (1%)13 (19%) Conclusions Dietetic intervention within a SU4CS programme led to improved nutritional status, demonstrating the opportunity to improve nutrition in preparation for major cancer surgery. Other metrics captured during the programme include SARC-F, EQ-5D, HAD scores which are currently being interrogated and may support additional benefits of the SU4CS programme.