Characteristic Gut Microbiota in PCOS-IR Patients and Its Association with Endocrine Features

Our findings show that gut microbiota disturbance leads to endocrine and metabolic features resembling PCOS-IR. The gut microbiota, particularly <i>Fusobacterium</i>, could serve as a clinical marker and potential therapeutic target for people with PCOS-IR. This study provides mechanistic insights into how gut microbiota contributes to PCOS-IR pathogenesis.

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Publication Details

Journal
Diabetes Metabolic Syndrome and Obesity
Published
2025-12-01
DOI
https://doi.org/10.2147/dmso.s561487
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

Characteristic Gut Microbiota in PCOS-IR Patients and Its Association with Endocrine Features

Dongxia Zhai, Chaoqin Yu, Mengcheng Cai, YanNing Yao et al.
Diabetes Metabolic Syndrome and Obesity
Gut microbiota and health
article

Characteristic Gut Microbiota in PCOS-IR Patients and Its Association with Endocrine Features

Dongxia Zhai, Chaoqin Yu, Mengcheng Cai, YanNing Yao, Anran XUE, Jin Yu, Xinyang Ren, Ling Zhou, Wenyi Liang
article en

Abstract

Our findings show that gut microbiota disturbance leads to endocrine and metabolic features resembling PCOS-IR. The gut microbiota, particularly <i>Fusobacterium</i>, could serve as a clinical marker and potential therapeutic target for people with PCOS-IR. This study provides mechanistic insights into how gut microbiota contributes to PCOS-IR pathogenesis.

Diabetes Metabolic Syndrome and ObesityVol. Volume 18
Shanghai Business School (CN), Second Military Medical University (CN), Southwest Medical University (CN), Changhai Hospital (CN)
Shanghai Municipal Health Commission, National Natural Science Foundation of China
Openalex Percentile: Top 35%
Gut microbiota and health
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