Characteristic Gut Microbiota in PCOS-IR Patients and Its Association with Endocrine Features
Our findings show that gut microbiota disturbance leads to endocrine and metabolic features resembling PCOS-IR. The gut microbiota, particularly <i>Fusobacterium</i>, could serve as a clinical marker and potential therapeutic target for people with PCOS-IR. This study provides mechanistic insights into how gut microbiota contributes to PCOS-IR pathogenesis.
Authors
- Dongxia Zhai
- Chaoqin Yu
- Mengcheng Cai
- YanNing Yao
- Anran XUE
- Jin Yu
- Xinyang Ren
- Ling Zhou
- Wenyi Liang
Institutions
- Shanghai Business School (CN)
- Second Military Medical University (CN)
- Southwest Medical University (CN)
- Changhai Hospital (CN)
Publication Details
- Journal
- Diabetes Metabolic Syndrome and Obesity
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/dmso.s561487
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China