Predicting bevacizumab efficacy: the emerging role of ACTL6B in colorectal cancer

ACTL6B, alone or combined with S1PR3 and PPP2R2B, constitutes a robust biomarker panel for stratifying CRC patients likely to benefit from bevacizumab, warranting prospective clinical qualification.

Authors

Xiaoshuai Zhou (ORCID: https://orcid.org/0009-0009-9924-8148)
JF Zhu
Xia Weng

Institutions

Ningbo University (CN)
Ningbo No. 2 Hospital (CN)

Publication Details

Journal: Journal of Gastrointestinal Oncology
Published: 2025-12-01
DOI: https://doi.org/10.21037/jgo-2025-373
Primary Topic: Colorectal Cancer Treatments and Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

Predicting bevacizumab efficacy: the emerging role of ACTL6B in colorectal cancer

Xiaoshuai Zhou, JF Zhu, Xia Weng

Dec 1, 2025

Journal of Gastrointestinal Oncology

Colorectal Cancer Treatments and Studies

article

Predicting bevacizumab efficacy: the emerging role of ACTL6B in colorectal cancer

Xiaoshuai Zhou, JF Zhu, Xia Weng

December 1, 2025article en

Abstract

ACTL6B, alone or combined with S1PR3 and PPP2R2B, constitutes a robust biomarker panel for stratifying CRC patients likely to benefit from bevacizumab, warranting prospective clinical qualification.

Journal of Gastrointestinal OncologyVol. 16(6)

Ningbo University (CN), Ningbo No. 2 Hospital (CN)

Good health and well-being

Openalex Percentile: Top 30%

Colorectal Cancer Treatments and Studies

DOI Open Access PDF OpenAlex

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Predicting bevacizumab efficacy: the emerging role of ACTL6B in colorectal cancer — Xiaoshuai Zhou, JF Zhu, et al. · Journal of Gastrointestinal Oncology (2025) | TGRS Research Map | TGRS