Traditional and Novel Virologic Markers for Functional Cure and HBeAg Loss with Pegylated Interferon in Chronic Hepatitis B: A Systematic Review and Meta-analysis
HBsAg decline at week 24 and baseline HBsAg levels are better predictors of functional cure than novel virologic markers, while on-treatment HBV RNA and HBeAg levels and dynamic changes are the most reliable indicators for HBeAg loss.
Authors
- Qi Zheng
- Mindie H. Nguyen
- Long-Fei Wang
- Jing Chen
- Ying Zhang
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Stanford Medicine (US)
- Stanford University (US)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2025-12-26
- DOI
- https://doi.org/10.14218/jcth.2025.00443
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00