Joint Exposure to Multiple Air Pollutants, Genetic Susceptibility, and Risk of Heart Failure in Cancer Patients: A Prospective Study in UK Biobank

Our findings indicate that long-term combined exposure to multiple air pollutants, including PM<sub>2.5</sub>, PM<sub>10</sub>, NO<sub>2</sub>, and NO<sub>x</sub>, is associated with an elevated risk of new-onset HF in cancer patients, particularly among individuals with a high genetic predisposition to the disease.

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Publication Details

Journal
Clinical Cardiology
Published
2025-12-01
DOI
https://doi.org/10.1002/clc.70235
Primary Topic
Health, Environment, Cognitive Aging
Type
article
Field-Weighted Citation Impact
0.00
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article

Joint Exposure to Multiple Air Pollutants, Genetic Susceptibility, and Risk of Heart Failure in Cancer Patients: A Prospective Study in UK Biobank

Ga Wu, Peinan Tu, Deng Yingyu, Xueqi Xiao et al.
Clinical Cardiology
Health, Environment, Cognitive Aging
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Joint Exposure to Multiple Air Pollutants, Genetic Susceptibility, and Risk of Heart Failure in Cancer Patients: A Prospective Study in UK Biobank

Ga Wu, Peinan Tu, Deng Yingyu, Xueqi Xiao, Xin Lin, H. He, Kaiyi Chi, Lixiao Huang, Long Pan, Peipei Wang, Yu Yang, Liyu Guo, W. Zhong, Jianpeng Liang, Meiting Jiao, Wenjuan Jiang, Kepeng Wei, Binghua Zhang, Tianwang Guan
article en

Abstract

Our findings indicate that long-term combined exposure to multiple air pollutants, including PM<sub>2.5</sub>, PM<sub>10</sub>, NO<sub>2</sub>, and NO<sub>x</sub>, is associated with an elevated risk of new-onset HF in cancer patients, particularly among individuals with a high genetic predisposition to the disease.

Clinical CardiologyVol. 48(12)
Inserm (FR), Université Paris Cité (FR), Sorbonne Université (FR), Second Affiliated Hospital of Guangzhou Medical University (CN), Sorbonne Paris Cité (FR), Centre de Recherche des Cordeliers (FR), Shenzhen Bao'an District People's Hospital (CN), Southern Medical University Shenzhen Hospital (CN), Guangdong Academy of Medical Sciences (CN), Southern Medical University (CN), Guangzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 32%
Health, Environment, Cognitive Aging
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