Is Pelvic-Paraaortic Lymphadenectomy Necessary in Endometrial Cancer? A Retrospective Analysis of Lymph Node Metastasis Predictors and Outcomes in 275 Patients

In this retrospective study, multivariate analyses showed that LVSI and depth of myometrial invasion were independent risk factors for pelvic lymph node involvement. Pelvic lymph node positivity was also a predictive factor for paraaortic lymph node involvement. There is no consensus on the surgical staging of endometrial cancer. Surgical staging therefore serves to identify patients for whom treatment for extrauterine disease is indicated and to avoid overtreatment of the majority of patients with localised disease. Routine paraaortic lymphadenectomy may not be necessary in patients without pelvic LN metastasis.