Glutaryl-CoA dehydrogenase: a key biomarker linking lysine degradation to hepatocellular carcinoma metastasis and prognosis via NF-KB signaling pathway
Inhibition of the lysine degradation pathway facilitates HCC metastasis and was involved in immune microenvironment remodeling. Additionally, GCDH may serve as a biomarker for predicting HCC metastasis and prognosis.
Authors
- Sheng Tai
- Z Li
- S. F. Yu
- Shizhuan Huang
- Y. Yu
- Dehai Wu
- Qiuhui Hu
Institutions
- Harbin Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Journal of Gastrointestinal Oncology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.21037/jgo-2025-355
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00