Survival outcomes of patients after liver transplantation for patients with hepatocellular carcinoma exceeding the Hangzhou criteria

For patients exceeding the Hangzhou criteria, those with an AFP level ≤1,000 ng/mL can still achieve acceptable long-term prognosis after LT. Administration of metformin has a strong positive association with longer recurrence-free survival. The patient criteria for selection for LT can be tentatively expanded.

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Publication Details

Journal
Journal of Gastrointestinal Oncology
Published
2025-12-01
DOI
https://doi.org/10.21037/jgo-2025-aw-864
Primary Topic
Metabolism, Diabetes, and Cancer
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article
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article

Survival outcomes of patients after liver transplantation for patients with hepatocellular carcinoma exceeding the Hangzhou criteria

Shu-tong Lu, J. Chen, Hani M. Wadei, Zhiping Huang et al.
Journal of Gastrointestinal Oncology
Metabolism, Diabetes, and Cancer
article

Survival outcomes of patients after liver transplantation for patients with hepatocellular carcinoma exceeding the Hangzhou criteria

Shu-tong Lu, J. Chen, Hani M. Wadei, Zhiping Huang, Meng-Chao Wang, Rendong Liu, Feng Huo, Bao Zhang, Xiaoyu Tan, Shaoping Wang, Diamantis I. Tsilimigras, Qing Ouyang, Jin Du, Yu-Jian Zheng
article en

Abstract

For patients exceeding the Hangzhou criteria, those with an AFP level ≤1,000 ng/mL can still achieve acceptable long-term prognosis after LT. Administration of metformin has a strong positive association with longer recurrence-free survival. The patient criteria for selection for LT can be tentatively expanded.

Journal of Gastrointestinal OncologyVol. 16(6)
Jacksonville College (US), The Ohio State University Wexner Medical Center (US), Mayo Clinic in Florida (US)
Good health and well-being
Openalex Percentile: Top 36%
Metabolism, Diabetes, and Cancer
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Survival outcomes of patients after liver transplantation for patients with hepatocellular carcinoma exceeding the Hangzhou criteria — Shu-tong Lu, J. Chen, et al. · Journal of Gastrointestinal Oncology (2025) | TGRS Research Map | TGRS