Celastrol exerts a neuroprotective effect by inhibiting necroptosis and inflammation in intracerebral hemorrhage-induced brain injury
These findings suggest that celastrol mitigates ICH-induced injury by concurrently inhibiting necroptotic pathways and inflammatory responses.
Authors
- Wei Ma (ORCID: https://orcid.org/0000-0001-5195-1541)
- Yu Guo (ORCID: https://orcid.org/0000-0002-1752-1254)
- Fangbao Li
- Fengzhen Xiong
- Jiayuan Ge
- Zhenggang Lu (ORCID: https://orcid.org/0000-0001-8468-6617)
- Hengzhu Zhang
- Yi Liu (ORCID: https://orcid.org/0000-0002-6727-4407)
- Xingdong Wang
Institutions
- Dalian Medical University (CN)
- Northern Jiangsu People's Hospital (CN)
Publication Details
- Journal
- Neuroreport
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1097/wnr.0000000000002237
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00