CTG-Insight: A Multi-Agent Interpretable LLM Framework for Cardiotocography Analysis and Classification

Remote fetal monitoring technologies are becoming increasingly common. Yet, most current systems offer limited interpretability, leaving expectant parents with raw cardiotocography (CTG) data that is difficult to understand. In this work, we present CTG-Insight, a multi-agent LLM system that provides structured interpretations of fetal heart rate (FHR) and uterine contraction (UC) signals. Drawing from established medical guidelines, CTG-Insight decomposes each CTG trace into five medically defined features: baseline, variability, accelerations, decelerations, and sinusoidal pattern, each analyzed by a dedicated agent. A final aggregation agent synthesizes the outputs to deliver a holistic classification of fetal health, accompanied by a natural language explanation. We evaluate CTG-Insight on the NeuroFetalNet Dataset and compare it against deep learning models and the single-agent LLM baseline. Results show that CTG-Insight achieves state-of-the-art accuracy (96.4%) and F1-score (97.8%) while producing transparent and interpretable outputs. This work contributes an interpretable and extensible CTG analysis framework.

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Published
2025-10-12
DOI
https://doi.org/10.1145/3714394.3756343
Primary Topic
Neonatal and fetal brain pathology
Type
article
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article

CTG-Insight: A Multi-Agent Interpretable LLM Framework for Cardiotocography Analysis and Classification

Black Sun, Die Hu
Neonatal and fetal brain pathology
article

CTG-Insight: A Multi-Agent Interpretable LLM Framework for Cardiotocography Analysis and Classification

Black Sun, Die Hu
article en

Abstract

Remote fetal monitoring technologies are becoming increasingly common. Yet, most current systems offer limited interpretability, leaving expectant parents with raw cardiotocography (CTG) data that is difficult to understand. In this work, we present CTG-Insight, a multi-agent LLM system that provides structured interpretations of fetal heart rate (FHR) and uterine contraction (UC) signals. Drawing from established medical guidelines, CTG-Insight decomposes each CTG trace into five medically defined features: baseline, variability, accelerations, decelerations, and sinusoidal pattern, each analyzed by a dedicated agent. A final aggregation agent synthesizes the outputs to deliver a holistic classification of fetal health, accompanied by a natural language explanation. We evaluate CTG-Insight on the NeuroFetalNet Dataset and compare it against deep learning models and the single-agent LLM baseline. Results show that CTG-Insight achieves state-of-the-art accuracy (96.4%) and F1-score (97.8%) while producing transparent and interpretable outputs. This work contributes an interpretable and extensible CTG analysis framework.

Anhui University of Science and Technology (CN), Aarhus University (DK)
Quality Education
Openalex Percentile: Top 18%
Neonatal and fetal brain pathology
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