Causal Relationship Between Butyrate and Dyspepsia: Evidence From Two‐Sample Mendelian Randomization Analysis of <scp>CSF</scp> Metabolites
Our study provides the first genetic evidence linking elevated CSF butyrate levels to a reduced risk of dyspepsia, highlighting a potential neuroprotective role within the gut-brain axis.
Authors
- Yujie Jiang (ORCID: https://orcid.org/0009-0002-9644-5305)
- Heran Zhou
- T. Zhu
- Yichen Cai (ORCID: https://orcid.org/0000-0003-1161-3382)
- Hancheng FAN
- Jia Zhu
- Guoxiang Fu
- Caixia Sheng
Institutions
- Zhejiang Chinese Medical University (CN)
- Sir Run Run Shaw Hospital (CN)
Publication Details
- Journal
- JGH Open
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/jgh3.70333
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00