Construction and Evaluation of a Chimeric Japanese Encephalitis Virus Vaccine Candidate Strain with Chaoyang Virus as the Backbone
The results demonstrate that the CYV-based CYV-JEV candidate vaccine demonstrates both safety and efficacy, representing a promising alternative to attenuated JEV vaccines, with CYV showing potential as a safe and effective universal flavivirus vaccine backbone.
Authors
- Yuzhong Feng
- G. Liu
- Xu Huang (ORCID: https://orcid.org/0000-0002-9197-0808)
- J Cui
- Qingyang Wang (ORCID: https://orcid.org/0000-0002-9999-3019)
- Xianghua Xiong
- Haolong Dong
- Xianzhu Xia
- Yupeng Li
- Huipeng Chen
Institutions
- Anhui Medical University (CN)
- Academy of Military Medical Sciences (CN)
Publication Details
- Journal
- Vaccines
- Published
- 2025-12-26
- DOI
- https://doi.org/10.3390/vaccines14010030
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00