Molecular Pathways Underlying Neurodegenerative and Vascular Pathologies in Alzheimer's Disease

We identified distinct pathways associated with AD-related genes and vascular genes, highlighting divergent biological mechanisms driving disease progression. These insights may guide the development of targeted therapeutic strategies for AD with varying vascular involvement.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70855_107579
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Molecular Pathways Underlying Neurodegenerative and Vascular Pathologies in Alzheimer's Disease

Annie Lee, Richard Mayeux, Badri N. Vardarajan, David A. A. Bennett et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Molecular Pathways Underlying Neurodegenerative and Vascular Pathologies in Alzheimer's Disease

Annie Lee, Richard Mayeux, Badri N. Vardarajan, David A. A. Bennett, Minghua Liu
article en

Abstract

We identified distinct pathways associated with AD-related genes and vascular genes, highlighting divergent biological mechanisms driving disease progression. These insights may guide the development of targeted therapeutic strategies for AD with varying vascular involvement.

Alzheimer s & DementiaVol. 21(S1)
Rush University Medical Center (US), NewYork–Presbyterian Hospital (US), Columbia University Irving Medical Center (US), Columbia University (US)
Openalex Percentile: Top 32%
Alzheimer's disease research and treatments
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