86 Recurrence of Gallstone Related Disease Following Endoscopic Retrograde Cholangiopancreatography and Sphincterotomy (ERCP ST) for Common Bile Duct (CBD) Stones Prior to Laparoscopic Cholecystectomy (LC): A Retrospective Analysis of a Single Distri

Abstract Aim Evidence on timing of LC post ERCP for CBD stones is limited. Our aim was to determine the probability of recurrent gallstone events following ERCP ST in patients who did not have LC and to determine the interval from index ERCP at which they occur. Method We analysed ERCP procedures performed between 1/1/2022 and 31/12/2023 in a single DGH. We included patients who had ERCP ST for gallstone disease and did not have LC prior to index ERCP. We followed up patients to the date of LC or until 8/11/2024. Statistical analysis was performed using Welch’s t-test, Fisher’s exact test and chi-squared test. Results 142 patients were included (54% female). For 79 (56%) patients who did not have LC the median follow up was 647 days (131-1039). 17 (12%) suffered from further episodes of gallstone disease. 15 (88%) required hospital admissions. The median length of stay was 9 days (3-22 days). The median time from index ERCP to developing a gallstone complication was 86 days (11-592). Five (29%) developed recurrent gallstone events within 6 weeks. Univariable analyses showed no significant association between recurrence and age (mean 69.0 vs 66.9 years; p = 0.72), gender (p = 1.00), or post-ERCP complications (p = 1.00). Patients who had index ERCP ST for cholangitis had a higher recurrence rate of 21% (p = 0.09). Conclusions The probability of developing gallstone events following ERCP ST was 8% per year. 3.5% of patients suffered from a recurrent event within six weeks. Fit patients should be offered early LC.