The Human Respiratory Virome in Health and Disease: Interactions, Dysbiosis, and Methodological Challenges (Advanced Genetics 4/06)

The Dual Landscape of the Respiratory Virome The bronchial tree is the lung's forest, hosting a complex microbial world. This cover art captures the delicate balance of the respiratory virome. On one side, lush foliage signifies a diverse, healthy ecosystem in homeostasis. On the other, withered branches reveal the impact of viral proliferation and dysbiosis. In article 202500022, Yao et al. comprehensively review the respiratory virome, covering its healthy composition, host-microbiota interactions, and disease-associated alterations, while addressing methodological challenges and future clinical applications.