Siji Kangbingdu Mixture Ameliorates LPS-Induced Acute Lung Injury by Downregulating the TNF/IL-17 Signaling Pathways: A Comprehensive Study Using Transcriptomics, Network Pharmacology and Experimental Verification

SJM has the potential to inhibit the progression of ALI, and its mechanism of action may involve the TNF and IL-17 signaling downregulation.

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Publication Details

Journal
Journal of Inflammation Research
Published
2025-12-01
DOI
https://doi.org/10.2147/jir.s562152
Primary Topic
Andrographolide Research and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Siji Kangbingdu Mixture Ameliorates LPS-Induced Acute Lung Injury by Downregulating the TNF/IL-17 Signaling Pathways: A Comprehensive Study Using Transcriptomics, Network Pharmacology and Experimental Verification

Liu Yuxi, K. M. LONG, Hong Zhang, Huiying Zhou et al.
Journal of Inflammation Research
Andrographolide Research and Applications
article

Siji Kangbingdu Mixture Ameliorates LPS-Induced Acute Lung Injury by Downregulating the TNF/IL-17 Signaling Pathways: A Comprehensive Study Using Transcriptomics, Network Pharmacology and Experimental Verification

Liu Yuxi, K. M. LONG, Hong Zhang, Huiying Zhou, Bo Wang, Yuan Wang
article en

Abstract

SJM has the potential to inhibit the progression of ALI, and its mechanism of action may involve the TNF and IL-17 signaling downregulation.

Journal of Inflammation ResearchVol. Volume 18
Northwest University (CN), Shaanxi Provincial Hospital of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 23%
Andrographolide Research and Applications
DOIOpen Access PDFOpenAlex
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Siji Kangbingdu Mixture Ameliorates LPS-Induced Acute Lung Injury by Downregulating the TNF/IL-17 Signaling Pathways: A Comprehensive Study Using Transcriptomics, Network Pharmacology and Experimental Verification — Liu Yuxi, K. M. LONG, et al. · Journal of Inflammation Research (2025) | TGRS Research Map | TGRS