Draft Genome Sequence and Virulence Factors of <i>Fusobacterium vincentii</i> KCOM 2880 Isolated from Human Subgingival Plaque

Fusobacterium vincentii, recently reclassified to species level based on genomic analyses, is a Gramnegative anaerobic bacterium implicated in periodontal diseases and various oral infections [1].Strain JS61 (= KCOM 2880) was isolated from subgingival plaque of a 61-year-old male periodontitis patient at the Dental Clinic, Korea University Anam Hospital, Seoul, South Korea in November 2014 (IRB No. ED14239).The strain was deposited in the Korean Collection for Oral Microbiology (WDCM 1178, Republic of Korea).The strain was grown in brain heart infusion (BHI, Difco Laboratories, USA) broth [1] and incubated in an anaerobic chamber (Model Bactron I, USA) with an atmosphere of 10% H 2 , 10% CO 2 , and 80% N 2 at 37 for 1-2 days.Fusobacterium vincentii, recently reclassified from subspecies to species status, is an oral anaerobe associated with periodontal disease.We report the draft genome sequence of strain KCOM 2880, isolated from human subgingival plaque.The genome (2,054,883 bp, three contigs) encodes 1,969 genes, including 1,848 proteincoding sequences, 56 pseudogenes, 65 RNA genes, and one CRISPR array.Virulence factor analysis identified 77 genes, including four FadA adhesins, five cell surface proteins, seven autotransporters, serine proteases, a type II secretion system, and TonB-dependent and hemin receptors.These results may provide genomic insights into the pathogenic potential of F. vincentii.