Genomic characterization and comparative analysis of multidrug-resistant Escherichia coli ST361 from urban wetland

The study highlights the presence of E. coli ST361, a multidrug-resistant, high-risk clone, in wetlands. Wetlands may act as "hotspots" for the persistence and spread of MDR E. coli, which is concerning as antibiotics are becoming less effective as last-resort treatments. The finding of ST361 in lakes underscores the "One Health" concept, emphasizing that antibiotic resistance impacts human, animal, and environmental health. To combat rising antimicrobial resistance (AMR) in aquatic environments, comprehensive strategies such as advanced wastewater treatment, stricter regulations on antibiotic use, public awareness campaigns, and routine environmental monitoring are crucial.