Treat-to-target optimization of biologic therapy is effective on endoscopic and histologic outcomes in a real-life cohort of ulcerative colitis—the TACTIC-UC study
In UC patients with quiescent or mild symptoms but active endoscopic inflammation, endoscopy-guided optimization of biologics is effective in achieving deeper inflammatory control, supporting its integration into T2T strategies.
Authors
- Elisabetta Sauta (ORCID: https://orcid.org/0000-0002-7830-988X)
- Saverio D’Amico (ORCID: https://orcid.org/0000-0003-1877-8497)
- Luisa Bertin (ORCID: https://orcid.org/0009-0001-9816-4171)
- Luca Ranucci
- Benedetta Masoni
- Arianna Dal Buono (ORCID: https://orcid.org/0000-0002-8543-4355)
- Roberto Gabbiadini (ORCID: https://orcid.org/0000-0002-7277-1053)
- Giulia Migliorisi
- Laura S. Loy (ORCID: https://orcid.org/0000-0002-3867-2078)
- Mattia Delleani (ORCID: https://orcid.org/0009-0004-1136-0930)
- Alessandro Armuzzi
- Matteo Della Porta
- Cristina Bezzio
- Victor Savevski
- giuseppe Privitera
Institutions
- Humanitas University (IT)
- University of Padua (IT)
- Azienda Ospedale - Università Padova (IT)
- Fondazione Humanitas per la Ricerca (IT)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Journal of Crohn s and Colitis
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1093/ecco-jcc/jjaf239
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00