The potential of real-time ultrasound screen viewing to reduce pain and anxiety symptoms during transperineal prostate biopsy under local anesthesia: a prospective non-randomized observational study

Real-time ultrasound screen viewing during TPBx under local anesthesia was associated with statistically significant reductions in pain and anxiety scores. However, considering the study's non-randomized design and the modest magnitude of VAS change, the clinical relevance of this difference should be interpreted with caution. This simple and low-cost approach may help improve patient comfort and procedural compliance, but further randomized studies are needed to confirm its effectiveness.