Outcomes of cranial nerve disorders in pharyngo-laryngeal herpes zoster: A retrospective study of 34 cases at a single institution

Pharyngo-laryngeal HZ is a distinct clinical entity typically manifesting as cranial polyneuropathy. The IX and X nerves are most often involved, with laryngeal paralysis associated with poorer outcomes. A substantial proportion of patients experience severe or prolonged dysphagia, necessitating nutritional support and rehabilitation. The frequent occurrence of zoster sine herpete highlights the critical role of serological testing in diagnosis. These findings emphasize that pharyngo-laryngeal HZ can cause severe, lasting morbidity, warranting early recognition, aggressive treatment, and preventive strategies, including zoster vaccination.

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Journal
Auris Nasus Larynx
Published
2025-12-28
DOI
https://doi.org/10.1016/j.anl.2025.12.014
Primary Topic
Facial Nerve Paralysis Treatment and Research
Type
article
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article

Outcomes of cranial nerve disorders in pharyngo-laryngeal herpes zoster: A retrospective study of 34 cases at a single institution

Yasushi Furuta, Michiya Matsumura, Hiroko Yanagi, Hiroki Sato et al.
Auris Nasus Larynx
Facial Nerve Paralysis Treatment and Research
article

Outcomes of cranial nerve disorders in pharyngo-laryngeal herpes zoster: A retrospective study of 34 cases at a single institution

Yasushi Furuta, Michiya Matsumura, Hiroko Yanagi, Hiroki Sato, Kanoko Minoshima
article en

Abstract

Pharyngo-laryngeal HZ is a distinct clinical entity typically manifesting as cranial polyneuropathy. The IX and X nerves are most often involved, with laryngeal paralysis associated with poorer outcomes. A substantial proportion of patients experience severe or prolonged dysphagia, necessitating nutritional support and rehabilitation. The frequent occurrence of zoster sine herpete highlights the critical role of serological testing in diagnosis. These findings emphasize that pharyngo-laryngeal HZ can cause severe, lasting morbidity, warranting early recognition, aggressive treatment, and preventive strategies, including zoster vaccination.

Auris Nasus LarynxVol. 53(1)
Teine Keijinkai Hospital (JP), Hokkaido University Hospital (JP)
Zero hunger
Openalex Percentile: Top 30%
Facial Nerve Paralysis Treatment and Research
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Outcomes of cranial nerve disorders in pharyngo-laryngeal herpes zoster: A retrospective study of 34 cases at a single institution — Yasushi Furuta, Michiya Matsumura, et al. · Auris Nasus Larynx (2025) | TGRS Research Map | TGRS