The effect of serum eosinophilia and lymphocytosis on functional outcomes of Hirschsprung disease patients after Duhamel procedure.

The majority of patients had normal eosinophil levels (78.8%) and normal lymphocyte counts (96.2%). Functional outcomes revealed that 49 patients (94.2%) had no voluntary bowel movements (VBM), 45 patients (86.5%) did not experience constipation, and 48 subjects (92.3%) had no soiling issues. There was no significant association was found between eosinophilia and functional outcomes in Hirschsprung disease patients after Duhamel procedure (p > 0.05). Similarly, there was no significant association between lymphocytosis and functional outcomes in these patients following Duhamel procedure (p > 0.05) CONCLUSION: The functional outcomes of patients with Hirschsprung disease post-Duhamel procedure at our institution are favorable with most having normal eosinophil and lymphocyte counts. Eosinophilia and lymphocytosis might not significantly affect the outcomes of Hirschsprung disease patients after undergoing the Duhamel procedure at Dr. Sardjito Hospital.