Inflammatory stress on induced neurons carrying Parkinson's disease‐associated LRRK2 Mutations
Our data indicates a LRRK2 genotype related response of LRRK2 neurons to IFNγ stimulus. This data lays the groundwork for future studies to dissect mechanisms of neuronal vulnerability in PD and the interplay between LRRK2 mutations and disease pathways.
Authors
- Adamantios Mamais (ORCID: https://orcid.org/0000-0002-5546-7084)
- Paramita Chakrabarty (ORCID: https://orcid.org/0000-0002-6226-3776)
- Matthew J. LaVoie (ORCID: https://orcid.org/0000-0002-2583-1578)
- Jose Torrellas
- ARAVINDRAJA CHAIRMANDURAI
Institutions
- University of Florida (US)
- Florida College (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70855_107448
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00