Intravenous delivery of mesenchymal stromal cells reverses Müller cell endoplasmic reticulum stress in diabetic retinopathy
Single Intravenous injection of hUC-MSC to DM animals could alleviate DR via reducing Müller cell and endothelial cell activation and ER stress, and thus might represent a promising therapy for DR.
Authors
- Jun Ma (ORCID: https://orcid.org/0000-0002-1796-8283)
- Matthew D. Griffin (ORCID: https://orcid.org/0000-0002-8701-8056)
- Seán O. Hynes (ORCID: https://orcid.org/0000-0002-3092-7945)
- Sanbing Shen (ORCID: https://orcid.org/0000-0002-8217-9811)
- T. Liu
- Boxin Liu (ORCID: https://orcid.org/0009-0001-3519-5034)
- Ruiyun Guo
- Jingjing He
- Yukun Liu
- Timothy O’Brien
- Wei Yan
- Yan Liu
- Rui Ping
Institutions
- Hebei Medical University (CN)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Third Hospital of Hebei Medical University (CN)
- Hebei Science and Technology Department (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1186/s13287-025-04876-4
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00