Literature Review on the Regulatory Effects of Hydrogen Sulfide in Non-Alcoholic Fatty Liver Disease (NAFLD)

Hydrogen sulfide (H<sub>2</sub>S), a gaseous signal, exerts multi-mechanistic protective effects in NAFLD. Current limitations include unclear signaling mechanisms and lack of targeted delivery systems. Future research should focus on stage-specific mechanisms, optimized H<sub>2</sub>S donors, and combination therapies for NAFLD treatment.

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Publication Details

Journal
Hepatic Medicine Evidence and Research
Published
2025-12-01
DOI
https://doi.org/10.2147/hmer.s574921
Primary Topic
Sulfur Compounds in Biology
Type
article
Field-Weighted Citation Impact
0.00

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article

Literature Review on the Regulatory Effects of Hydrogen Sulfide in Non-Alcoholic Fatty Liver Disease (NAFLD)

Shan Zhou, Baoyi Sun, Jun Yan, Guanning Zhong et al.
Hepatic Medicine Evidence and Research
Sulfur Compounds in Biology
article

Literature Review on the Regulatory Effects of Hydrogen Sulfide in Non-Alcoholic Fatty Liver Disease (NAFLD)

Shan Zhou, Baoyi Sun, Jun Yan, Guanning Zhong, Zhaoying Xuan, Xiaolei Sun
article en

Abstract

Hydrogen sulfide (H<sub>2</sub>S), a gaseous signal, exerts multi-mechanistic protective effects in NAFLD. Current limitations include unclear signaling mechanisms and lack of targeted delivery systems. Future research should focus on stage-specific mechanisms, optimized H<sub>2</sub>S donors, and combination therapies for NAFLD treatment.

Hepatic Medicine Evidence and ResearchVol. Volume 17
Nantong University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 32%
Sulfur Compounds in Biology
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