Transcription factor activity-based stratification reveals prognostic subtypes and immune landscape in neuroblastoma
TF activity profiling provides robust stratification for NB, integrating clinical prognostication and immune characterization. This study offers novel insights into TF-driven NB biology, with implications for targeted therapy and immunotherapeutic strategies.
Authors
- Xinyu Tian (ORCID: https://orcid.org/0000-0003-1247-6076)
- Yuren Xia
- Mingyou Gao (ORCID: https://orcid.org/0000-0001-8931-6164)
- Jie Li (ORCID: https://orcid.org/0000-0003-2343-1658)
- Ning Zhao (ORCID: https://orcid.org/0000-0003-3699-3369)
- Limeng Zhang (ORCID: https://orcid.org/0009-0005-2745-3813)
- Yun Liu
- Qiang Zhao
- Xin Li
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
Publication Details
- Journal
- Translational Pediatrics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.21037/tp-2025-aw-739
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00