The HPV-E7/miR-106a/RUNX3/TGF-β1 axis regulates malignant progression in both HPV-positive and negative head and neck squamous cell carcinoma
Our findings suggest that the E7/miR-106a/RUNX3/TGF-β1 axis modulates proliferation, migration, invasion, and apoptosis in HPV-positive versus negative HNSCC, implicating its pathogenic role in tumor progression.
Authors
- Yangchun Zhang (ORCID: https://orcid.org/0000-0002-0540-9070)
- Chunlin Zhang (ORCID: https://orcid.org/0000-0003-0425-3569)
- Yongxu Wu
- Yifei Liu (ORCID: https://orcid.org/0000-0003-1030-8618)
- Zhaohui Liu (ORCID: https://orcid.org/0000-0003-4658-0744)
- Xu Li
- Chunlei Li
Institutions
- Zunyi Medical University (CN)
- Affiliated Hospital of Zunyi Medical College (CN)
Publication Details
- Journal
- Molecular and Cellular Probes
- Published
- 2025-12-27
- DOI
- https://doi.org/10.1016/j.mcp.2025.102060
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00